Repairing the Skin Barrier in Atopic Dermatitis

Patients with atopic dermatitis have a not only global reduction in the 3 key physiologic lipids but also a further reduction in the amount of ceramide.1 Ceramides are pivotal components of the extracellular lamellae that control barrier function. Ceramides, when used in a triple-lipid mixture that includes cholesterol and free fatty acids, are highly effective in restoring barrier function in atopic dermatitis.

The ceramide-dominant formulation of EpiCeram addresses the specific deficiency2 in ceramides in atopic dermatitis.

1. Man MQ, et al. J Invest Dermatol 1996;106:1096-1101

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